⮝ Full datasets listing
PXD062434
PXD062434 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Single-cell proteome atlas of aging mouse microglia |
| Description | In this study, we established a high-throughput workflow for unbiased, simultaneous profiling of the single-cell proteome and cellular morphology, achieving high sensitivity and reproducibility. Using this workflow, we analyzed male mouse microglia sorted from hippocampus and prefrontal cortex at three distinct ages including 2, 14, and 24 months, generating a high-quality proteomic dataset (3,184 single cells after quality control; average of 1,339 protein groups per cell) with robust consistency. |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-27 |
| AnnouncementXML | Submission_2026-06-16_20:13:33.589.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Haoran Zhang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | monohydroxylated residue; acetylated residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-31 20:03:19 | ID requested | |
| ⏵ 1 | 2026-06-16 20:13:34 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Single-cell proteomics (SCP), Mass spectrometry (MS), Brain aging, Microglia heterogeneity |
Contact List
| Cheng Li | |
|---|---|
| contact affiliation | Peking University |
| contact email | cheng_li@pku.edu.cn |
| lab head | |
| Haoran Zhang | |
| contact affiliation | Peking University |
| contact email | 2301110581@stu.pku.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
