PXD062430

PXD062430 is an original dataset announced via ProteomeXchange.

Title	Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator
Description	This project aims to understand the ssDNA-mediated allosteric activation mechanism of DriD, a novel Caulobacter crescentus transcription activator. Using LC-MS/MS, the major proteolytic cleavage site within DriD was identified, providing insight into its solvent accessible regions.
HostingRepository	PRIDE
AnnounceDate	2025-04-14
AnnouncementXML	Submission_2025-04-14_13:19:09.493.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Emily Cannistraci
SpeciesList	scientific name: Caulobacter vibrioides; NCBI TaxID: 155892;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-31 18:12:09	ID requested
⏵ 1	2025-04-14 13:19:09	announced

Dataset with its publication pending

submitter keyword: LC-MS/MS, DriD, Caulobacter crescentus, transcription activator

Maria A Schumacher
contact affiliation	Duke University Department of Biochemistry
contact email	maria.schumacher@duke.edu
lab head
Emily Cannistraci
contact affiliation	Duke University
contact email	emily.cannistraci@duke.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD062430

PRIDE project URI

• PRIDE
  1. PXD062430
     1. Label: PRIDE project
     2. Name: Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator