PXD062361 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A Metal-Dependant Formate Dehydrogenase Advances the Formate Bio-economy |
Description | In this manuscript a multi-subunit metal dependent FDH is functionally expressed in a strain of E. coli engineered to assimilate all energy and biomass from formate. The replacement of the previously described FDH with this new, faster FDH allows for improved growth parameters rivaling natural formatotrophs for the first time. This new, robsulty growing formatotrophic E. coli was engineered to produce mevalonate and achieved the highest reported titer for any bioproduct from formate in fed batch mode. Finally the authors explored bioproducion from electrochemically-derived and lignin-derived formate, demonstrating the first example of a bioproduct produced using liginin-derived formate as a feedstock. |
HostingRepository | PRIDE |
AnnounceDate | 2025-06-06 |
AnnouncementXML | Submission_2025-06-06_14:45:03.743.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Christopher Petzold |
SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Exploris 480 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2025-03-28 13:50:44 | ID requested | |
⏵ 1 | 2025-06-06 14:45:04 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: isoprenol, mevalonate,Bakar Bioenginuity,Formate dehydrogenase, formate, reductive glycine pathway, bioproducion |
Contact List
Christopher J. Petzold |
contact affiliation | Staff Scientist Biological Systems & Engineering Division Lawrence Berkeley National Laboratory Berkeley CA 94720 |
contact email | cjpetzold@lbl.gov |
lab head | |
Christopher Petzold |
contact affiliation | Lawrence Berkeley National Laboratory |
contact email | cjpetzold@lbl.gov |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD062361 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062361
- Label: PRIDE project
- Name: A Metal-Dependant Formate Dehydrogenase Advances the Formate Bio-economy