PXD062316

PXD062316 is an original dataset announced via ProteomeXchange.

Title	Analysis of the altered t-cell proteome in proteasome impaired patients
Description	Proteome analysis of samples derived from patients with impaired protasome functionality.
HostingRepository	PRIDE
AnnounceDate	2025-12-15
AnnouncementXML	Submission_2025-12-15_06:17:38.870.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Leif Steil
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-27 09:15:46	ID requested
⏵ 1	2025-12-15 06:17:39	announced

Wolfgramm S, Alehashemi S, Wendlandt M, Thiel FG, de Jesus AA, Papendorf JJ, Wolfgramm H, Alvarez FL, Borngr, ä, ber E, Uss K, Bhuyan F, Metpally A, Steil L, Hentschker C, Venz S, Abdulla RA, Poirier L, Friend C, Casta FC, Horkayne-Szakaly I, Akoghlanian S, Mustillo PJ, Abraham RS, Bastard P, Moura TCL, Dorna MB, Kozu KT, Kers J, Teng YKO, Bredius RGM, Palmblad K, Horne A, Brodin P, Blanco-Lobo P, Bernabeu-Wittel J, Fernandez-Silveira L, Neth O, Pagnier A, Boursier G, Tusseau M, Huizinga TWJ, Fournier B, Neven B, V, ö, lker U, Santen GWE, Brenchley JM, Calvo KR, Kleiner D, Ebstein F, Kr, ü, ger E, Goldbach-Mansky R, A de novo dominant-negative PSMB8 mutation causes severe CANDLE/PRAAS due to arrested proteasome biogenesis. Ann Rheum Dis, ():(2025) [pubmed]

10.1016/j.ard.2025.10.021;

submitter keyword: PROTEASOME,HUMAN

Uwe Völker
contact affiliation	University Medicine Greifswald, Interfaculty Institute of Genetics and Functional Genomics, Department of Functional Genomics
contact email	voelker@uni-greifswald.de
lab head
Leif Steil
contact affiliation	Universitätsmedizin Greifswald KöR Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung
contact email	steil@uni-greifswald.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD062316

PRIDE project URI

• PRIDE
  1. PXD062316
     1. Label: PRIDE project
     2. Name: Analysis of the altered t-cell proteome in proteasome impaired patients