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PXD062286

PXD062286 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAlterations in IP6K2 Protein Interactions in HCT116 Cells Pre- and Post-Dextran Sulfate Sodium Exposure
DescriptionUsing HCT116 wild-type cells as a blank control, we divided 3×Flag-IP6K2 knockin HCT116 cells into two groups: a negative control (untreated) and an experimental group (treated with 3% DSS for 4 hours). After treatment, cells were lysed, and Flag-tagged IP6K2 and its interacting proteins were immunoprecipitated (IP) using anti-Flag beads. Subsequently, bound proteins were competitively eluted with a FLAG peptide. The eluates were then analyzed by mass spectrometry (MS) to identify DSS-induced alterations in the IP6K2 interactome.
HostingRepositoryiProX
AnnounceDate2025-03-26
AnnouncementXMLSubmission_2025-03-26_20:52:18.863.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHongyun Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-03-26 20:52:07ID requested
⏵ 12025-03-26 20:52:19announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: HCT116, DSS, IP6K2
Contact List
Feng Rao
contact affiliationSouthern University of Science and Technology
contact emailraof@sustech.edu.cn
lab head
Hongyun Zhang
contact affiliationSouthern University of Science and Technology
contact email12131327@mail.sustech.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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