PXD062283

PXD062283 is an original dataset announced via ProteomeXchange.

Title	Molecular Landscape of Atherosclerotic Plaque Progression: Insights from Proteomics
Description	This dataset comprises proteomic profiles of 87 human carotid atherosclerotic plaques from patients undergoing carotid endarterectomy (CEA). The study employed an integrated approach using Data Independent Acquisition (DIA) proteomics. A total of 87 human carotid plaques were analyzed to identify and quantify protein expression. The proteomic analysis of the 87 carotid plaques revealed 6143 proteins, highlighting diverse expression profiles across different plaque stages.
HostingRepository	iProX
AnnounceDate	2025-03-26
AnnouncementXML	Submission_2025-05-19_00:19:40.670.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuyao Feng
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-26 20:45:44	ID requested
⏵ 1	2025-05-19 00:19:41	announced

Wang C, Feng Y, Liu X, Sun H, Guo Z, Shao J, Li K, Chen J, Shu K, Kong D, Wang J, Li Y, Lei X, Li C, Liu B, Sun W, Lai Z, Molecular landscape of atherosclerotic plaque progression: insights from proteomics, single-cell transcriptomics and genomics. BMC Med, 23(1):254(2025) [pubmed]

submitter keyword: Carotid Atherosclerotic Plaque, DIA, carotid artery stenosis

Wei Sun
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College
contact email	sunwei1018@sina.com
lab head
Yuyao Feng
contact affiliation	Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College
contact email	yuyao.feng@foxmail.com
dataset submitter

iProX dataset URI