PXD062047
PXD062047 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | RSDR, a Novel Potential Biomarker, Protects Against AKI by Interacting with hnRNPK to Regulate DHODH-Mediated Ferroptosis |
| Description | Molecular analyses—including RNA immunoprecipitation, pull-down assays, mass spectrometry, and chromatin immunoprecipitation sequencing—demonstrated that RSDR and hnRNPK stabilize each other, forming a positive feedback loop that amplifies DHODH expression. |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-19 |
| AnnouncementXML | Submission_2025-08-20_19:16:28.746.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fan Cheng |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-19 19:16:47 | ID requested | |
| 1 | 2025-03-19 19:16:59 | announced | |
| ⏵ 2 | 2025-08-20 19:16:29 | announced | 2025-08-21: Add info. |
Publication List
| Li B, Lin F, Song B, Han S, Ye Z, Sun Y, Wang P, Xia Y, Yu W, Zhou X, Cheng F, The long non-coding RNA RSDR protects against acute kidney injury in mice by interacting with hnRNPK to regulate DHODH-mediated ferroptosis. Nat Commun, 16(1):7483(2025) [pubmed] |
Keyword List
| submitter keyword: Acute kidney injury, lncRNA, hnRNPK, DHODH, Ferroptosis, Biomarker |
Contact List
| Fan Cheng | |
|---|---|
| contact affiliation | Renmin Hospital of Wuhan University |
| contact email | urology1969@aliyun.com |
| lab head | |
| Fan Cheng | |
| contact affiliation | Renmin Hospital of Wuhan University |
| contact email | urology1969@aliyun.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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