PXD062031 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Affinity purification-mass spectrometry to identify proteins interacting with Leishmania LINF_180011100 |
| Description | LINF_180011100 was validated as a drug target and resistance determinant for several antileishmanial aminopyrazole leads. Genetic fusion with an N-terminal green fluorescent protein (GFP) tag demonstrated that the protein primarily localizes in cytoplasmic/endocytic vesicles and revealed an impact of treatment with aminopyrazoles. To identify interacting partners of LINF_180011100, we exploited the fusion with GFP as an affinity tag for immunoprecipitation followed by LC–MS² analysis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-18 |
| AnnouncementXML | Submission_2026-08-18_07:00:31.892.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Sara Dufour |
| SpeciesList | scientific name: Leishmania infantum; NCBI TaxID: NEWT:5671; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-03-19 07:22:41 | ID requested | |
| ⏵ 1 | 2026-08-18 07:00:32 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: LINF_180011100,Leishmania, aminopyrazole target, endosomes, FYVE zinc finger domain |
Contact List
| Guy Caljon |
|---|
| contact affiliation | Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp |
| contact email | Guy.Caljon@uantwerpen.be |
| lab head | |
| Sara Dufour |
|---|
| contact affiliation | VIB-UGent |
| contact email | sara.dufour@vib-ugent.be |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD062031 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD062031
- Label: PRIDE project
- Name: Affinity purification-mass spectrometry to identify proteins interacting with Leishmania LINF_180011100
