PXD061985 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | An unbiased molecular characterisation of peripartum cardiomyopathy identfies mast cell chymase as a new diagnostic candidate and therapeutic target |
| Description | Peripartum cardiomyopathy (PPCM) is a rare form of acute heart failure that develops in women towards the end of pregnancy or early in the postpartum period. Despite clinical similarities to dilated cardiomyopathy of other etiologies (non-peripartum cardiomyopathy; NPCM), the molecular mechanisms driving PPCM remain poorly understood. To characterize disease-specific proteomic remodeling, we conducted deep proteomic profiling of heart tissue from PPCM patients, NPCM patients, and healthy organ donors. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-12_06:29:53.252.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jonathan Achter |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-03-18 10:04:32 | ID requested | |
| ⏵ 1 | 2026-01-12 06:29:53 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, Heart, Cardiomyopathy, Peripartum |
Contact List
| Alicia Lundby |
|---|
| contact affiliation | Cardiac Proteomics & Systems Biology Group, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen |
| contact email | alicia.lundby@sund.ku.dk |
| lab head | |
| Jonathan Achter |
|---|
| contact affiliation | University of Copenhagen |
| contact email | jonathan.achter@sund.ku.dk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD061985 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061985
- Label: PRIDE project
- Name: An unbiased molecular characterisation of peripartum cardiomyopathy identfies mast cell chymase as a new diagnostic candidate and therapeutic target
