PXD061824 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Short-chain fatty acids synergistically interact with doxorubicin against gastric adenocarcinoma cells |
| Description | Short-chain fatty acids (SCFAs) are microbial metabolites, also known as postbiotics, produced by the gut microbiotame, playing essential rolesessential in maintaining gut health and exerting potential anticancer effects. This study investigates the antiproliferative effects of short-chain fatty acids (SCFAs) salts—magnesium acetate (A), sodium propionate (P), and sodium butyrate (B)—and their combinations with doxorubicin (Dox) in AGS gastric adenocarcinoma cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-19 |
| AnnouncementXML | Submission_2026-01-18_17:13:08.260.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Muhammad Alsherbiny |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-03-14 03:43:09 | ID requested | |
| ⏵ 1 | 2026-01-18 17:13:09 | announced | |
Publication List
| 10.3390/ijms27010362; |
| Eladwy RA, Fares M, Alsherbiny MA, Chang D, Li CG, Bhuyan DJ, Postbiotics Combination Synergises the Antiproliferative Effects of Doxorubicin in Gastric Cancer Cells: A Cellular and Molecular Deep Dive. Int J Mol Sci, 27(1):(2025) [pubmed] |
Keyword List
| submitter keyword: Postbiotics, Apoptosis, Doxorubicin, Proteomics,Gastric cancer |
Contact List
| Deep Bhuyan |
|---|
| contact affiliation | NICM HRI, Western Sydney University |
| contact email | d.bhuyan@westernsydney.edu.au |
| lab head | |
| Muhammad Alsherbiny |
|---|
| contact affiliation | 1) Freedman Foundation Metabolomics Facility, Innovation Centre, Victor Chang Cardiac Research Institute UNSW
2) Pharmacognosy Department, Faculty of Pharmacy, Cairo University |
| contact email | muhammad.alsherbiny@pharma.cu.edu.eg |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD061824 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061824
- Label: PRIDE project
- Name: Short-chain fatty acids synergistically interact with doxorubicin against gastric adenocarcinoma cells
