PXD061745

PXD061745 is an original dataset announced via ProteomeXchange.

Title	Label-free quantitative proteomic analysis for normal and inflamed colonic mucosa from patients with ulcerative colitis
Description	Label-free quantitative proteomic analysis for clinical tissues of 5 normal and 5 inflamed colonic mucosa. The EASY-nLC 1200 system and Q Exactive Plus were used for peptides detection. A total of 4102 proteins were identified, and 2713 proteins were quantified. According to the criterion fold change > 2 and adjusted P value less than 0.05, we found 159 differential protein.
HostingRepository	iProX
AnnounceDate	2025-03-12
AnnouncementXML	Submission_2025-08-10_21:21:54.782.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei Zhou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-12 01:05:07	ID requested
1	2025-06-19 18:42:12	announced
⏵ 2	2025-08-10 21:21:55	announced	2025-08-11: Add info.

Liu S, Sun H, Du Z, Lu S, Wang C, Zhang Y, Luo Z, Wang L, Fan Z, Wei P, Yan Y, Zhang J, Yin S, Liu T, He Q, Guo X, Ding K, Zhou J, Hua H, Yu C, Xu W, Shan J, Li Y, Xu Y, Shen X, Cao G, Zhou W, Metabolomics and proteomics reveal blocking argininosuccinate synthetase 1 alleviates colitis in mice. Nat Commun, 16(1):6983(2025) [pubmed]

submitter keyword: Label-free quantification, Ulcerative colitis, Inflamed colonic mucosa

Wei Zhou
contact affiliation	China Pharmaceutical University
contact email	zhouwei19860506@163.com
lab head
Wei Zhou
contact affiliation	China Pharmaceutical University
contact email	zhouwei19860506@163.com
dataset submitter

iProX dataset URI