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PXD061741

PXD061741 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEstablishment of biomarkers to predict response to glucocorticoids for thyroid eye disease by DIA proteome analysis.
DescriptionThe standard treatment for thyroid eye disease is glucocorticoid administration, however its response varies from case to case. In recent years, treatment of thyroid eye disease has evolved dramatically, and the efficacy of several agents is being demonstrated. If steroid resistance is identified prior to treatment, the quality of care can be improved by using other agents as first-line therapy. We performed DIA proteome analysis on pretreatment sera of glucocorticoids response and resistance patients to search for candidate biomarkers of therapeutic response. Sera from healthy subjects and those with Graves' disease without thyroid eye disease are also analyzed together as controls.
HostingRepositoryjPOST
AnnounceDate2026-03-12
AnnouncementXMLSubmission_2026-03-11_08:00:04.379.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMatsuzawa Kazuhiko
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; unknown modification
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-03-12 00:25:13ID requested
12026-03-11 08:00:04announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Thyroid eye disease, glucocorticoids, Biomarker of therapeutic response
Contact List
Kazuhiko Matsuzawa
lab head
Matsuzawa Kazuhiko
contact affiliationTottori university, faculty of medicine
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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