PXD061725

PXD061725 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Astral-DIA Proteomics Deciphers the Molecular Landscape of Human Spermatozoa: A Comprehensive Quantitative Proteomic Characterization of Sperm Function and Fertility Potential
Description	Male infertility is fundamentally rooted in developmental defects of germ cells and associated molecular dysregulation, yet the underlying mechanisms remain poorly understood. Data-independent acquisition (DIA) has emerged as a powerful tool in discovery proteomics, enabling the identification of disease biomarkers, therapeutic targets, and molecular pathways with high precision and reproducibility. T
HostingRepository	PRIDE
AnnounceDate	2025-03-12
AnnouncementXML	Submission_2025-03-11_21:40:16.924.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ran Kong
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-11 14:35:36	ID requested
⏵ 1	2025-03-11 21:40:17	announced

Publication List

Perez-Riverol Y, Bandla C, Kundu DJ, Kamatchinathan S, Bai J, Hewapathirana S, John NS, Prakash A, Walzer M, Wang S, Vizca, í, no JA, The PRIDE database at 20 years: 2025 update. Nucleic Acids Res, 53(D1):D543-D553(2025) [pubmed]
10.1093/nar/gkae1011;

Perez-Riverol Y, Bandla C, Kundu DJ, Kamatchinathan S, Bai J, Hewapathirana S, John NS, Prakash A, Walzer M, Wang S, Vizca, í, no JA, The PRIDE database at 20 years: 2025 update. Nucleic Acids Res, 53(D1):D543-D553(2025) [pubmed]

10.1093/nar/gkae1011;

Keyword List

submitter keyword: Astral-DIA
Proteomics
Human Spermatozoa

submitter keyword: Astral-DIA

Proteomics

Human Spermatozoa

Contact List

Ran Kong
contact affiliation	Institute of Advanced Clinical Medicine, Biomedical Engineering Department, International Cancer Institute, Peking University, Beijing, China.
contact email	597381620@qq.com
lab head
Ran Kong
contact affiliation	Institute of Advanced Clinical Medicine, Biomedical Engineering Department, International Cancer Institute, Peking University, Beijing, China.
contact email	597381620@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD061725
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD061725

PRIDE project URI

Repository Record List

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