⮝ Full datasets listing
PXD061717
PXD061717 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of tofersen PD-response biomarkers in VALOR clinical trial CSF via multiplexed quantitative proteomics |
| Description | TMT dataset profiling longitudinally-collected CSF from SOD1-ALS subjects who received either tofersen (SOD1-ASO) or placebo treatments during the Phase 3 VALOR clinical trial (NCT02623699) |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-01-22 |
| AnnouncementXML | Submission_2026-01-22_12:18:45.238.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Amanda Guise |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Carbamidomethyl; TMTpro; Oxidation |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-11 11:55:55 | ID requested | |
| ⏵ 1 | 2026-01-22 12:18:45 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: amyotrophic lateral sclerosis (ALS), cerebrospinal fluid (CSF) proteomics, pharmacodynamic-response, biomarkers, human clinical trial, DatasetType:Proteomics |
Contact List
| Danielle Graham | |
|---|---|
| contact affiliation | Biogen |
| contact email | danielle.graham@biogen.com |
| lab head | |
| Amanda Guise | |
| contact affiliation | Biogen |
| contact email | amanda.guise@biogen.com |
| lab head | |
| Amanda Guise | |
| contact affiliation | Biogen |
| contact email | amanda.guise@biogen.com |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v09/MSV000097291/ |
