PXD061667

PXD061667 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Crosslinking/mass spectrometry analysis of Human Separase-Scc1-fusion and cohesin SMC1/SMC3 complexes
Description	In this study, we employed the photoactivatable crosslinker (sulfo-SDA) to investigate protein-protein interaction between human Separase-Scc1 fusion protein and SMC1/SMC3 cohesin subunits complex in the presence of DNA.
HostingRepository	PRIDE
AnnounceDate	2025-08-28
AnnouncementXML	Submission_2025-08-27_21:25:53.161.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD061667
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kitaik Lee
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-03-10 17:42:15	ID requested
⏵ 1	2025-08-27 21:25:53	announced

Publication List

10.6019/PXD061667;

10.6019/PXD061667;

Keyword List

submitter keyword: sulfo-SDA, SMC1, SMC3, Scc1,Separase, XLMS

submitter keyword: sulfo-SDA, SMC1, SMC3, Scc1,Separase, XLMS

Contact List

Francis J. O'Reilly
contact affiliation	Center for Structural Biology, Center for Cancer Research, National Cancer Institute (NCI)
contact email	oreillyfj@nih.gov
lab head
Kitaik Lee
contact affiliation	Center for Structural Biology, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health, Frederick, MD 21702-1201, USA
contact email	kitaik.lee@nih.gov
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD061667
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD061667

PRIDE project URI

Repository Record List

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