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PXD061373

PXD061373 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation
DescriptionMDA-MB-231 cells with expression of Flag-GPX4 were treated with IFNg. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
HostingRepositoryiProX
AnnounceDate2025-03-01
AnnouncementXMLSubmission_2025-05-14_21:21:27.964.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPeixiang Zheng
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
Instrument4800 Plus MALDI TOF/TOF; LTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-03-02 20:13:42ID requested
12025-05-14 21:21:29announced
Publication List
Zheng P, Hu Z, Shen Y, Gu L, Ouyang Y, Duan Y, Ji G, Dong B, Lin Y, Wen T, Tian Q, Hou Y, Zhou Q, Sun X, Chen X, Wang KL, Luo S, Wu S, Sun Y, Li M, Xiao L, Wu Q, Meng Y, Liu G, Wang Z, Bai X, Duan S, Ding Y, Bi Y, Wang Y, Li G, Liu X, Lu Z, Wu X, Tang Z, Xu D, PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation. Nat Chem Biol, ():(2025) [pubmed]
Keyword List
submitter keyword: PSAT1, GPX4, ferroptosis, Lipid ROS, cancer immunotherapy
Contact List
Daqian Xu
contact affiliationZhejiang university
contact emailxudaqian@zju.edu.cn
lab head
Peixiang Zheng
contact affiliationZhejiang university
contact emailpeixiangzheng7@gmail.com
dataset submitter
Full Dataset Link List
iProX dataset URI