PXD061373
PXD061373 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation |
| Description | MDA-MB-231 cells with expression of Flag-GPX4 were treated with IFNg. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis. |
| HostingRepository | iProX |
| AnnounceDate | 2025-03-01 |
| AnnouncementXML | Submission_2025-05-14_21:21:27.964.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Peixiang Zheng |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | 4800 Plus MALDI TOF/TOF; LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-03-02 20:13:42 | ID requested | |
| ⏵ 1 | 2025-05-14 21:21:29 | announced |
Publication List
| Zheng P, Hu Z, Shen Y, Gu L, Ouyang Y, Duan Y, Ji G, Dong B, Lin Y, Wen T, Tian Q, Hou Y, Zhou Q, Sun X, Chen X, Wang KL, Luo S, Wu S, Sun Y, Li M, Xiao L, Wu Q, Meng Y, Liu G, Wang Z, Bai X, Duan S, Ding Y, Bi Y, Wang Y, Li G, Liu X, Lu Z, Wu X, Tang Z, Xu D, PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation. Nat Chem Biol, ():(2025) [pubmed] |
Keyword List
| submitter keyword: PSAT1, GPX4, ferroptosis, Lipid ROS, cancer immunotherapy |
Contact List
| Daqian Xu | |
|---|---|
| contact affiliation | Zhejiang university |
| contact email | xudaqian@zju.edu.cn |
| lab head | |
| Peixiang Zheng | |
| contact affiliation | Zhejiang university |
| contact email | peixiangzheng7@gmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
