PXD061285

PXD061285 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Endosomal chloride/proton exchangers need inhibitory TMEM9 β-subunits for regulation and prevention of disease-causing overactivity
Description	Multi-epitope affinity purification mass spectrometry (meAP-MS) analysis of TMEM9-, TMEM9B- and CLC3- associated proteins from solubilized mouse brain membranes identified chloride channel subtypes CLCN3, 4 and 5 as exclusive interaction partners of TMEM9 and TMM9B.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_07:48:22.114.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD061285
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Alexander Haupt
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-27 15:01:39	ID requested
⏵ 1	2025-05-07 07:48:22	announced

Publication List

10.6019/PXD061285;
10.1038/s41467-025-58546-3;
Planells-Cases R, Vorobeva V, Kar S, Schmitt FW, Schulte U, Schrecker M, Hite RK, Fakler B, Jentsch TJ, -subunits for regulation and prevention of disease-causing overactivity. Nat Commun, 16(1):3117(2025) [pubmed]

10.6019/PXD061285;

10.1038/s41467-025-58546-3;

Planells-Cases R, Vorobeva V, Kar S, Schmitt FW, Schulte U, Schrecker M, Hite RK, Fakler B, Jentsch TJ, -subunits for regulation and prevention of disease-causing overactivity. Nat Commun, 16(1):3117(2025) [pubmed]

Keyword List

submitter keyword: AP-MS, chloride channels, membrane protein complex, auxiliary subunits,mouse brain, protein-protein interactions

submitter keyword: AP-MS, chloride channels, membrane protein complex, auxiliary subunits,mouse brain, protein-protein interactions

Contact List

Prof. Dr. Bernd Fakler
contact affiliation	Institute of Physiology II, Universität Freiburg, Germany
contact email	bernd.fakler@physiologie.uni-freiburg.de
lab head
Alexander Haupt
contact affiliation	University of Freiburg, Germany
contact email	alexander.haupt@physiologie.uni-freiburg.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD061285
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD061285

PRIDE project URI

Repository Record List

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