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PXD061188

PXD061188 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleWu Selective Inhibition of matrix mechanosensing AP-MS
DescriptionThe .d files acquired in data-independent mode were analyzed using Spectronaut v 19.1 (Biognosys AG, Schlieren, Switzerland) with the directDIA+ feature against the Uniprot Homo sapiens protein database. Proteolysis with Trypsin was assumed to be semi-specific, allowing for N-ragged cleavage with up to two missed cleavage sites, with a PSM false discovery rate (FDR) of 1%. Data filtering was based on the Q Value, and global normalization was utilized. Cysteine modified with iodoacetamide was set as a fixed modification. Variable modifications included oxidation of methionine and tryptophan, deamidation of asparagine and glutamine, and phosphorylation of serine, threonine, and tyrosine.
HostingRepositoryMassIVE
AnnounceDate2025-03-03
AnnouncementXMLSubmission_2025-03-03_11:35:16.726.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterArianne Caudal
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListPhospho; Carbamidomethyl; Oxidation; Deamidated:18O(1)
InstrumenttimsTOF Ultra
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-02-25 11:28:52ID requested
12025-03-03 11:35:17announced
Publication List
no publication
Keyword List
submitter keyword: affinity pull down, DatasetType:Proteomics
Contact List
Arianne Caudal
contact affiliationStanford University
contact emailacaudal@stanford.edu
lab head
Arianne Caudal
contact affiliationStanford University
contact emailacaudal@stanford.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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