PXD061115

PXD061115 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic Analysis of Huh7, HIEC6, and NCI-H295R cells using High-affinity anti-Golm1 mAb by IP-MS.
Description	we conducted IP-MS strategy to screen its interacting proteins. High-affinity anti-Golm1 mAb and IgG were used in multiple cell lines including Huh7, HIEC6, and NCI-H295R cells. Proteins with more than two peptide segments enriched or exclusively within the Golm1 group were identified as putative interacting partners of Golm1.
HostingRepository	PRIDE
AnnounceDate	2026-03-23
AnnouncementXML	Submission_2026-03-22_17:13:11.721.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ruzhou Zhao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Homo sapiens; NCBI TaxID: NCBITaxon:9606;
ModificationList	acetylated residue
Instrument	Bruker Daltonics timsTOF series

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-23 19:43:28	ID requested
⏵ 1	2026-03-22 17:13:12	announced

Publication List

10.1016/j.jare.2025.07.003;
Zhen L, Min M, Mo X, Zhao G, Li H, Liu M, Wan L, Yang X, Huang L, Zhang Y, Gao Q, Zhong H, Qiang G, Wu F, Xie Q, Wei C, Zhao R, The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression. J Adv Res, 82():765-783(2026) [pubmed]

10.1016/j.jare.2025.07.003;

Zhen L, Min M, Mo X, Zhao G, Li H, Liu M, Wan L, Yang X, Huang L, Zhang Y, Gao Q, Zhong H, Qiang G, Wu F, Xie Q, Wei C, Zhao R, The GOLM1-ACLY pathway regulates macrophage-secreted EFEMP1 via H3K27ac modifications to drive tumor progression. J Adv Res, 82():765-783(2026) [pubmed]

Keyword List

submitter keyword: Golm1;IP-MS

submitter keyword: Golm1;IP-MS

Contact List

Congwen Wei
contact affiliation	Laboratory of Advanced Biotechnology, Beijing Institute of Biotechnology
contact email	weicongwen@aliyun.com
lab head
Ruzhou Zhao
contact affiliation	Laboratory of Advanced Biotechnology, Beijing Institute of Biotechnology
contact email	rz_zhao@yeah.net
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD061115
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD061115

PRIDE project URI

Repository Record List

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