PXD061070 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics Analysis of Skeletal Muscle in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy |
| Description | Prostate cancer (PCa) is the second most common cancer in men and negatively impact muscle mass, physical function, and patient-reported outcomes. Androgen deprivation therapy (ADT) is a widely used treatment for advanced disease, but it exacerbates these adverse effects. To investigate the molecular mechanisms underlying these changes in skeletal muscle, we performed muscle biopsies of the vastus lateralis for proteomic analysis from nineteen patients with PCa before starting ADT and after six months of treatment. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-06_17:18:41.407.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tomas Vaisar |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-21 14:51:58 | ID requested | |
| ⏵ 1 | 2026-09-06 17:18:42 | announced | |
Publication List
| 10.1038/s41467-026-73542-x; |
| Caeiro L, Anderson LJ, Dash A, Marcinek DJ, Kerr HL, Paulsen L, Miranda G, Jaramillo Quiroz S, Vaisar T, Krueger MA, Acosta-Vega NL, Gharib SA, Garcia JM, Muscle mitochondria, function, mass, and quality of life in prostate cancer during androgen deprivation therapy. Nat Commun, 17(1):(2026) [pubmed] |
Keyword List
| submitter keyword: Skeletal Muscle, Androgen Deprivation Therapy, data-independent acquisition, Prostate Cancer |
Contact List
| Tomas Vaisar |
|---|
| contact affiliation | UW Medicine Diabetes Institute, University of Washington, Seattle, WA 98109 |
| contact email | tvaisar@uw.edu |
| lab head | |
| Tomas Vaisar |
|---|
| contact affiliation | University of Washington |
| contact email | tvaisar@uw.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD061070 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD061070
- Label: PRIDE project
- Name: Proteomics Analysis of Skeletal Muscle in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
