PXD060995

PXD060995 is an original dataset announced via ProteomeXchange.

Title	YPTYF Alleviates DSS-Induced Colitis in Mice via SHP-2-Mediated ERK/NF-κB/p38MAPK Signaling Pathway Network Regulation
Description	Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease. Traditional drugs for the treatment of UC mainly by reducing the inflammaory response in UC or inhibiting the host immune response, but its long-term use may cause a variety of adverse reactions and a high relapse rate, which limits its clinical application. Yunpi Tongyi Formula (YPTYF), a classical Chinese patent medicine, is an effective treatment option for UC. However, the comprehensive ingredients in YPTYF and their multiple actions, as well as their underlying mechanisms against UC, have not been fully elucidated.
HostingRepository	iProX
AnnounceDate	2025-02-20
AnnouncementXML	Submission_2025-02-19_23:35:49.125.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qiongqiong Lu
SpeciesList	scientific name: Rattus rattus; NCBI TaxID: 10117;
ModificationList	acetylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-19 23:35:36	ID requested
⏵ 1	2025-02-19 23:35:49	announced

Dataset with its publication pending

submitter keyword: Yunpi Tongyi Formula, ulcerative colitis, intestinal mucosal barrier, anti-inflammatory, SHP-2

Fengliang Tian
contact affiliation	Chongqing Traditional Chinese Medicine Hospital
contact email	15923591761@163.com
lab head
Qiongqiong Lu
contact affiliation	Chongqing Traditional Chinese Medicine Hospital
contact email	luhaiyao788@163.com
dataset submitter

iProX dataset URI