PXD060920 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Caspase-8 expression and its Src dependent phosphorylation on Tyr380 triggers NRF2 signaling activation in glioblastoma |
| Description | Here we have employed quantitative mass spectrometry based phosphoproteomics and proteomics to characterise the impact of knocking-down the caspase 8 gene in glioblastoma cells. This strategy enabled the identification of the pathways and processes modulated by caspase 8. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-08 |
| AnnouncementXML | Submission_2025-12-07_18:53:07.408.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Francesca Sacco |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-18 08:52:36 | ID requested | |
| ⏵ 1 | 2025-12-07 18:53:08 | announced | |
Publication List
| Cirotti C, Di Girolamo C, Taddei I, Contadini C, Massacci G, Sacco F, Del Bufalo D, Salvatori I, Valle C, Baril, à D, Caspase-8 expression and its Src dependent phosphorylation on Tyrosine 380 triggers NRF2 signaling activation in glioblastoma. Cell Death Differ, 32(12):2355-2367(2025) [pubmed] |
| 10.1038/s41418-025-01542-3; |
Keyword List
| submitter keyword: glioblastoma, src, nrf2 |
Contact List
| Daniela Barila |
|---|
| contact affiliation | Department of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy. Laboratory of Cell Signaling, IRCCS-Fondazione Santa Lucia, 00179 Rome, Italy. |
| contact email | francesca.sacco@uniroma2.it |
| lab head | |
| Francesca Sacco |
|---|
| contact affiliation | University of Rome Tor Vergata |
| contact email | francesca.sacco@uniroma2.it |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD060920 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060920
- Label: PRIDE project
- Name: Caspase-8 expression and its Src dependent phosphorylation on Tyr380 triggers NRF2 signaling activation in glioblastoma
