PXD060895

PXD060895 is an original dataset announced via ProteomeXchange.

Title	Global profiling of the proteome and acetylome in mice with abdominal aortic aneurysms
Description	Abdominal Aortic Aneurysm (AAA) is a fatal vascular disease characterized by abnormal expansion of the arterial wall and a high risk of rupture. Current treatments for AAA primarily rely on surgical intervention, while effective pharmacological therapies have yet to be developed. The major bottlenecks include an incomplete understanding of the disease mechanisms and a lack of efficient therapeutic targets.This study conducted a comprehensive proteome and acetylome analysis of mice models with abdominal aortic aneurysm to identify the key proteins, signaling pathways, and acetylation modification patterns involved in the progress of AAA.
HostingRepository	iProX
AnnounceDate	2025-02-17
AnnouncementXML	Submission_2025-02-17_18:31:56.621.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Luyao Zhang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	acetylated residue
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-17 18:28:22	ID requested
⏵ 1	2025-02-17 18:31:57	announced

Dataset with its publication pending

submitter keyword: Abdominal Aortic Aneurysm;lysine acetylation

Juntao Yang
contact affiliation	Peking Union Medical College
contact email	superyjt79@163.com
lab head
Luyao Zhang
contact affiliation	Peking Union Medical College
contact email	z15937309531@163.com
dataset submitter

iProX dataset URI