PXD060832

PXD060832 is an original dataset announced via ProteomeXchange.

Title	Mitochondrial regulator PGC-1a in neuronal metabolism and brain aging
Description	The brain is a high-energy tissue, and brain-resident cell types are distinct in function and in metabolic requirements. The basis for cell-type-specific metabolic status and metabolic adaptation with age has not been well established. This proteomics analysis allows us to better understand how the brain responds to age, which we then leverage as an intervention point throughout the study. This dataset was derived from male mice at three different ages (10 months, 20 months, and 30 months).
HostingRepository	PRIDE
AnnounceDate	2025-02-14
AnnouncementXML	Submission_2025-02-14_10:40:12.560.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD060832
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Greg Sabat
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-14 09:51:50	ID requested
⏵ 1	2025-02-14 10:40:13	announced

10.6019/PXD060832;

submitter keyword: LC-MSMS,mouse, cortex, label-free, aging

Rozalyn Anderson
contact affiliation	Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison
contact email	rozalyn.anderson@wisc.edu
lab head
Greg Sabat
contact affiliation	University of Wisconsin
contact email	gsabat@wisc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD060832

PRIDE project URI

• PRIDE
  1. PXD060832
     1. Label: PRIDE project
     2. Name: Mitochondrial regulator PGC-1a in neuronal metabolism and brain aging