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PXD060832

PXD060832 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitochondrial regulator PGC-1a in neuronal metabolism and brain aging
DescriptionThe brain is a high-energy tissue, and brain-resident cell types are distinct in function and in metabolic requirements. The basis for cell-type-specific metabolic status and metabolic adaptation with age has not been well established. This proteomics analysis allows us to better understand how the brain responds to age, which we then leverage as an intervention point throughout the study. This dataset was derived from male mice at three different ages (10 months, 20 months, and 30 months).
HostingRepositoryPRIDE
AnnounceDate2025-02-14
AnnouncementXMLSubmission_2025-02-14_10:40:12.560.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD060832
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterGreg Sabat
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-02-14 09:51:50ID requested
12025-02-14 10:40:13announced
Publication List
10.6019/PXD060832;
Keyword List
submitter keyword: LC-MSMS,mouse, cortex, label-free, aging
Contact List
Rozalyn Anderson
contact affiliationDivision of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison
contact emailrozalyn.anderson@wisc.edu
lab head
Greg Sabat
contact affiliationUniversity of Wisconsin
contact emailgsabat@wisc.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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