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PXD060791

PXD060791 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDecoding the Heart Failure Peptidome
DescriptionTo systematically explore the low molecular peptidome, we conducted a cross-sectional mass spectrometry analysis from 486 patients with HF and 98 age-matched non-HF controls. We quantified 21 694 unique peptides in plasma, which were ranked according to (1) the relative upregulation in HF versus controls, (2) pattern similarity to bioactive peptides by an adapted machine learning method, and (3) association with clinical outcome.
HostingRepositoryPRIDE
AnnounceDate2026-04-25
AnnouncementXMLSubmission_2026-04-25_03:18:05.252.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChristian Madsen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListamidated residue; monohydroxylated residue; deaminated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-02-13 17:03:11ID requested
12026-04-25 03:18:05announced
Publication List
10.1161/CIRCHEARTFAILURE.125.013290;
Keyword List
submitter keyword: None
Contact List
Christian Toft
contact affiliationOmics Technologies, Research and early development, Novo Nordisk Måløv, Denmark
contact emailctom@novonordisk.com
lab head
Christian Madsen
contact affiliationGlobal Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.
contact emailctom@novonordisk.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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