PXD060721 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The Notch ligand Jagged1 regulates extracellular matrix production and organization in breast cancer |
| Description | Data-independent acquisition (DIA) mass spectrometry was used to study the effect of JAG1 protein in ECM organization in breast cancer. TNBC cell line samples including MDA-MB-231 cells (Jag1WT), JAG1 knock-out of MDA-MB-231 cells (Jag1KO), empty vector transfected to Jag1KO, and JAG1 rescued to Jag1KO cocultured with mouse embryonic fibroblasts (MEFs) as spheroids were used to compare the ECM proteins by mass spectrometry. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-09 |
| AnnouncementXML | Submission_2026-02-09_02:12:44.255.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ujjwal Suwal |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-12 05:52:59 | ID requested | |
| ⏵ 1 | 2026-02-09 02:12:44 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: ECM, DIA mass spectrometry, MDA-MB-231 human TNBC cells,Breast cancer, Mouse embryonic fibroblasts |
Contact List
| Jyrki Heino |
|---|
| contact affiliation | Department of Life Technologies and InFLAMES Research Flagship, University of Turku, FI-20014, Turku, Finland |
| contact email | jyrki.heino@utu.fi |
| lab head | |
| Ujjwal Suwal |
|---|
| contact affiliation | University of Turku |
| contact email | ujjwal.suwal@utu.fi |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD060721 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060721
- Label: PRIDE project
- Name: The Notch ligand Jagged1 regulates extracellular matrix production and organization in breast cancer
