PXD060687

PXD060687 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Differential analysis of nucleolar proteomics in metastatic breast cancer
Description	The nucleolus, responsible for ribosome biogenesis, acts as a key center for detecting and responding to cellular stress. Additionally, growing evidence suggests that ribosome biogenesis may play a significant role in promoting metastasis. A proteomic screen of nucleolar protein content between metastatic and non-metastatic breast cancers found that metastatic breast cancer cell lines have a unique nucleolar proteome signature as compared to non-metastatic breast cancer cell lines.
HostingRepository	PRIDE
AnnounceDate	2025-07-27
AnnouncementXML	Submission_2025-07-27_12:29:19.402.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD060687
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Brandon Metge
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-11 08:35:02	ID requested
⏵ 1	2025-07-27 12:29:19	announced

Publication List

10.6019/PXD060687;

10.6019/PXD060687;

Keyword List

submitter keyword: nucleolus,breast cancer, metastasis

submitter keyword: nucleolus,breast cancer, metastasis

Contact List

Lalita Samant
contact affiliation	University of Alabama at Birmingham, Department of Pathology, Division MCP, O'Neal Comprehensive Cancer Center
contact email	lalitasamant@uabmc.edu
lab head
Brandon Metge
contact affiliation	University of Alabama at Birmingham
contact email	brandonmetge@uabmc.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD060687
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD060687

PRIDE project URI

Repository Record List

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