PXD060676

PXD060676 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Persistent mirusvirus infection in the marine protist Aurantiochytrium
Description	The protist Aurantiochytrium limacinum possesses two mirusvirus-like genomic elements, one a circular episome (AurliV-1) and the other (AurliV-2) a chromosomal integrant. Here we show that genes in both genomes are expressed and virions containing mainly AurliV-1 DNA are produced under starvation conditions and when cells are cultured in standard growth medium. Of 67 AurliV-1-encoded proteins detected using proteomics, 48 are enriched under starvation conditions, including the structurally important major capsid and triplex proteins. Our results establish Aurantiochytrium as a model system for elucidating mirusvirus-host interactions and demonstrate persistent viral infection in a microbial eukaryote.
HostingRepository	PRIDE
AnnounceDate	2025-09-23
AnnouncementXML	Submission_2025-09-23_08:03:32.761.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Nikolaj Brask
SpeciesList	scientific name: Aurantiochytrium limacinum ATCC MYA-1381; NCBI TaxID: 717989;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-11 02:16:22	ID requested
⏵ 1	2025-09-23 08:03:33	announced

Publication List

10.21203/RS.3.RS-5686297/V1;

10.21203/RS.3.RS-5686297/V1;

Keyword List

submitter keyword: Mirusvirus,Aurantiochytrium

submitter keyword: Mirusvirus,Aurantiochytrium

Contact List

John Archibald
contact affiliation	Dalhousie University
contact email	jmarchib@dal.ca
lab head
Nikolaj Brask
contact affiliation	Lund University
contact email	nk377661@dal.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD060676
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD060676

PRIDE project URI

Repository Record List

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