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PXD060573

PXD060573 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA Technical Evaluation of Plasma Proteomics Technologies
DescriptionWe report a technical evaluation of six notable plasma proteomics technologies from recent years. Unenriched plasma, perchloric acid depletion, PreOmics ENRICHplus, Mag-Net, Seer Proteograph XT, and Olink Explore HT. The methods were compared on proteomic depth, reproducibility, linearity, tolerance to lipid interference, and limit of detection/quantification. We also tested the applicability of these methods for detecting differences between healthy and cancer groups in a non-small cell lung cancer cohort.
HostingRepositoryPRIDE
AnnounceDate2025-05-14
AnnouncementXMLSubmission_2025-05-13_16:14:30.018.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJoshua Coon
SpeciesList scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-02-07 01:14:38ID requested
12025-05-13 16:14:30announced
Publication List
10.1021/ACS.JPROTEOME.5C00221;
Keyword List
submitter keyword: Plasma, LC-MS, Proteomics
Contact List
Joshua J.
contact affiliationUniversity of Wisconsin-Madison, Morgridge Institute for Research
contact emailjcoon@chem.wisc.edu
lab head
Joshua Coon
contact affiliationUniversity of Wisconsin - Madison, Morgridge Institute for Research
contact emailjcoon@chem.wisc.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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