PXD060548 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of RNA-mediated interaction partners of endogenous IGF2BP3 in HCT116 cells in control and ER stress conditions |
| Description | IGF2BP3 is an RNA-binding protein that regulates mRNA stability, translation, and localization. IGF2BP3 binds to mRNAs encoding endoplasmic reticulum (ER) stress response proteins. To understand molecular mechanisms of its function we performed co-immunoprecipitation of the endogenous IGF2BP3 from colorectal carcinoma cell line HCT116 in control and ER stress conditions. RNase treatment was performed during washes to reveal RNA-bridged interactors. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-24 |
| AnnouncementXML | Submission_2026-07-23_23:40:17.086.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Markus Hartl |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-02-06 04:40:09 | ID requested | |
| ⏵ 1 | 2026-07-23 23:40:17 | announced | |
Publication List
Keyword List
| submitter keyword: IGF2BP3, ER stress, RNA-binding protein |
Contact List
| Dr Gülsün Elif Karagöz |
|---|
| contact affiliation | Max Perutz Labs, Vienna BioCenter Campus (VBC), 1030 Vienna, Austria; Austria Medical University of Vienna, Center for Medical Biochemistry, 1030 Vienna, Austria |
| contact email | guelsuen.karagoez@meduniwien.ac.at |
| lab head | |
| Markus Hartl |
|---|
| contact affiliation | Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr. Bohr-Gasse 9, Vienna, Austria |
| contact email | proteomics@maxperutzlabs.ac.at |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD060548 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD060548
- Label: PRIDE project
- Name: Identification of RNA-mediated interaction partners of endogenous IGF2BP3 in HCT116 cells in control and ER stress conditions
