PXD060503

PXD060503 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics of brown bear muscle during hibernation
Description	During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. For a better knowledge on proteome remodelling during hibernation, this study analysed the bear (Ursus arctos) skeletal muscle proteome using shotgun proteomics to compare hibernation to the summer-active period.
HostingRepository	PRIDE
AnnounceDate	2026-03-02
AnnouncementXML	Submission_2026-03-01_17:59:09.922.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabrice BERTILE
SpeciesList	scientific name: Ursus arctos (Brown bear) (Grizzly bear); NCBI TaxID: NEWT:9644;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-04 22:55:14	ID requested
⏵ 1	2026-03-01 17:59:11	announced

10.1111/apha.70177;

Bergouignan A, Noone J, Brun C, Cussonneau L, Geffroy A, Coudy-Gandilhon C, Chery I, Evans AL, Arnemo JM, Kindberg J, Gauquelin-Koch G, O'Gorman D, Lefai E, Bertile F, The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos). Acta Physiol (Oxf), 242(4):e70177(2026) [pubmed]

submitter keyword: LC-MSMS, metabolic depression,Bear, hibernation, muscle

Sarah Cianferani
contact affiliation	Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France
contact email	sarah.cianferani@unistra.fr
lab head
Fabrice BERTILE
contact affiliation	CNRS
contact email	fbertile@unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD060503

PRIDE project URI

• PRIDE
  1. PXD060503
     1. Label: PRIDE project
     2. Name: Quantitative proteomics of brown bear muscle during hibernation