PXD060475

PXD060475 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of STN1 interactiome in response to DNA damage in pancreatic cancer cells
Description	STN1 is known to play a critical role in DNA damage response, however, the mechanisms by which this is performed, specifically in the context of pancreatic cancer are not well understood. Here we studied the changes in STN1 interactome in control and in the response to DNA-damage causing stimuli.
HostingRepository	PRIDE
AnnounceDate	2025-10-13
AnnouncementXML	Submission_2025-10-12_17:38:39.110.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD060475
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Krystine Mansfield
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-02-04 12:30:06	ID requested
⏵ 1	2025-10-12 17:38:40	announced

Publication List

10.1093/nar/gkaf983;
10.6019/PXD060475;
Shen C, Cui T, Yang L, Gui L, Corrales-Guerrero S, Nair S, Li H, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Fernandez A, Ping X, Shen B, Stark JM, Williams TM, complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer. Nucleic Acids Res, 53(18):(2025) [pubmed]

10.1093/nar/gkaf983;

10.6019/PXD060475;

Shen C, Cui T, Yang L, Gui L, Corrales-Guerrero S, Nair S, Li H, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Fernandez A, Ping X, Shen B, Stark JM, Williams TM, complex-independent DNA double-strand break repair and cell cycle checkpoint maintenance in pancreatic cancer. Nucleic Acids Res, 53(18):(2025) [pubmed]

Keyword List

submitter keyword: IP-MS, DNA-damage repair, STN1, pancreatic cancer

submitter keyword: IP-MS, DNA-damage repair, STN1, pancreatic cancer

Contact List

Patrick Pirrotte
contact affiliation	Translational Genomics Research Institute
contact email	ppirrotte@tgen.org
lab head
Krystine Mansfield
contact affiliation	TGen
contact email	kgarcia@tgen.org
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD060475
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD060475

PRIDE project URI

Repository Record List

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