PXD060289

PXD060289 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mouse NIH-3T3 cohesin TurboID LC-MSMS
Description	The cohesin complex is a plieotropic regulator of genome structure and function. It is known to play a role in sister chromatin cohesin, DNA replication, DNA repair, and regulation of gene expression. Cohesin has several known interacting proteins that aid in the various roles within a nucleus, yet a comprehensive cohesin interactome has yet to be established. In this study, we utilized the biotin proximity ligation assay TurboID followed by LC-MS/MS in NIH-3T3 mouse fibroblast cells to identify novel proteins that interact with the cohesin complex.
HostingRepository	PRIDE
AnnounceDate	2025-06-02
AnnouncementXML	Submission_2025-06-02_05:48:08.476.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Natalie Rittenhouse
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	biotinylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-28 10:58:45	ID requested
⏵ 1	2025-06-02 05:48:08	announced

Publication List

10.1186/S13072-025-00596-4;

10.1186/S13072-025-00596-4;

Keyword List

submitter keyword: LC-MSMS,NIH-3T3, TurboID, cohesin

submitter keyword: LC-MSMS,NIH-3T3, TurboID, cohesin

Contact List

Jill M. Dowen
contact affiliation	University of North Carolina -- Chapel Hill Department of Biochemistry and Biophysics, Department of Biology
contact email	jdowen@unc.edu
lab head
Natalie Rittenhouse
contact affiliation	University of North Carolina -- Chapel Hill
contact email	nrittenhouse@unc.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD060289
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD060289

PRIDE project URI

Repository Record List

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