PXD060232
PXD060232 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Transgenic mice with myeloid-specific overexpression of human S100A12 |
Description | S100A12, a newly discovered member of the S100 family of calcium regulatory proteins, is located within the same gene cluster on chromosome 1q21 as other S100A family members. In humans, S100A12 is mainly secreted by neutrophils and monocytes, but can also be expressed by tissue cells, such as mucosal epithelial cells and keratinocytes. Rodents do not express S100A12. |
HostingRepository | iProX |
AnnounceDate | 2025-01-25 |
AnnouncementXML | Submission_2025-04-24_19:06:30.520.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xi Zhang |
SpeciesList | scientific name: Mus |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2025-01-27 03:00:42 | ID requested | |
1 | 2025-01-27 03:00:59 | announced | |
⏵ 2 | 2025-04-24 19:06:31 | announced | 2025-04-25: Add Publication. |
Publication List
Zhang X, Song H, Liu D, Cai Y, Liu Z, Zhang X, Zhao X, Zhang Y, Jing Q, Yan C, Han Y, S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis. Nat Commun, 16(1):1746(2025) [pubmed] |
Keyword List
submitter keyword: S100A12 |
Contact List
Yaling Han | |
---|---|
contact affiliation | State Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command |
contact email | hanyaling@163.net |
lab head | |
Xi Zhang | |
contact affiliation | State Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command |
contact email | cher0327@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |