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PXD060232

PXD060232 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTransgenic mice with myeloid-specific overexpression of human S100A12
DescriptionS100A12, a newly discovered member of the S100 family of calcium regulatory proteins, is located within the same gene cluster on chromosome 1q21 as other S100A family members. In humans, S100A12 is mainly secreted by neutrophils and monocytes, but can also be expressed by tissue cells, such as mucosal epithelial cells and keratinocytes. Rodents do not express S100A12.
HostingRepositoryiProX
AnnounceDate2025-01-25
AnnouncementXMLSubmission_2025-04-24_19:06:30.520.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXi Zhang
SpeciesList scientific name: Mus ; NCBI TaxID: 10088;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-27 03:00:42ID requested
12025-01-27 03:00:59announced
22025-04-24 19:06:31announced2025-04-25: Add Publication.
Publication List
Zhang X, Song H, Liu D, Cai Y, Liu Z, Zhang X, Zhao X, Zhang Y, Jing Q, Yan C, Han Y, S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis. Nat Commun, 16(1):1746(2025) [pubmed]
Keyword List
submitter keyword: S100A12
Contact List
Yaling Han
contact affiliationState Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command
contact emailhanyaling@163.net
lab head
Xi Zhang
contact affiliationState Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command
contact emailcher0327@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI