PXD060232

PXD060232 is an original dataset announced via ProteomeXchange.

Title	Transgenic mice with myeloid-specific overexpression of human S100A12
Description	S100A12, a newly discovered member of the S100 family of calcium regulatory proteins, is located within the same gene cluster on chromosome 1q21 as other S100A family members. In humans, S100A12 is mainly secreted by neutrophils and monocytes, but can also be expressed by tissue cells, such as mucosal epithelial cells and keratinocytes. Rodents do not express S100A12.
HostingRepository	iProX
AnnounceDate	2025-01-25
AnnouncementXML	Submission_2025-04-24_19:06:30.520.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xi Zhang
SpeciesList	scientific name: Mus ; NCBI TaxID: 10088;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-27 03:00:42	ID requested
1	2025-01-27 03:00:59	announced
⏵ 2	2025-04-24 19:06:31	announced	2025-04-25: Add Publication.

Zhang X, Song H, Liu D, Cai Y, Liu Z, Zhang X, Zhao X, Zhang Y, Jing Q, Yan C, Han Y, S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis. Nat Commun, 16(1):1746(2025) [pubmed]

submitter keyword: S100A12

Yaling Han
contact affiliation	State Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command
contact email	hanyaling@163.net
lab head
Xi Zhang
contact affiliation	State Key Laboratory of Frigid Zone Cardiovascular Disease, Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command
contact email	cher0327@qq.com
dataset submitter

iProX dataset URI