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PXD060218

PXD060218 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePlasma proteomics of Ghanian children from high malaria transmission (HMT) and low malaria transmission (LMT) zones
DescriptionWe performed a longitudinal study of the plasma proteome of children infected with malaria and residing in low or high malaria transmission areas in Ghana. A mass spectrometry-based approach was used to identify putative protein-based biomarkers and predictors of resistance to malaria. Our findings confirm earlier reports and identify putative signature proteins implicated in immune tolerance to malaria.
HostingRepositoryPRIDE
AnnounceDate2025-02-11
AnnouncementXMLSubmission_2025-02-10_19:49:20.057.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMehdi Bouhaddou
SpeciesList scientific name: Plasmodium falciparum; NCBI TaxID: 5833; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-26 21:35:03ID requested
12025-02-10 19:49:20announced
Publication List
Mohammed AM, Olwal CO, Fossati A, Nyakoe NK, Fabius JM, Gordon M, Polacco BJ, Swaney DL, Awandare GA, Krogan NJ, Bouhaddou M, Bediako Y, Malaria exposure remodels the plasma proteome of Ghanaian children. BMC Infect Dis, 25(1):157(2025) [pubmed]
10.1186/s12879-025-10495-4;
Keyword List
submitter keyword: Plasma, malaria, children, blood
Contact List
Mehdi Bouhaddou
contact affiliationDepartment of Microbiology, Immunology, and Molecular Genetics (MIMG) Institute for Quantitative and Computational Biosciences (QCBio) University of California, Los Angeles (UCLA)
contact emailmehdibouhaddou@gmail.com
lab head
Mehdi Bouhaddou
contact affiliationUCLA
contact emailbouhaddoulab@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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