⮝ Full datasets listing
PXD060136
PXD060136 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Identification of Novel Proteins in Primary and Secondary Membranous Nephropathy Using Laser Microdissection and Mass Spectrometry |
| Description | Membranous nephropathy (MN) is a major cause of nephrotic syndrome in adults and is defined by subepithelial immune complex deposits along the glomerular basement membrane. While primary (or idiopathic) MN often involves known autoantigens such as PLA2R and THSD7A, secondary MN can be associated with autoimmune diseases, infections (for example, hepatitis B or C), malignancies, and certain medications. Despite these discoveries, the detailed mechanisms underlying both primary and secondary MN remain insufficiently understood.　Recently, advances in liquid chromatography–mass spectrometry (LC-MS) have facilitated more extensive proteomic analyses, enabling the identification of potential novel proteins tied to MN pathogenesis. Such findings may not only enhance our understanding of the disease mechanisms involved in both primary and secondary MN but also guide future diagnostic and therapeutic innovations. |
| HostingRepository | jPOST |
| AnnounceDate | 2026-01-24 |
| AnnouncementXML | Submission_2026-01-23_07:00:05.477.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dedong Kang |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-01-24 00:11:14 | ID requested | |
| ⏵ 1 | 2026-01-23 07:00:06 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, kidney, renal biopsy, LCMS/MS |
Contact List
| Dedong Kang | |
|---|---|
| lab head | |
| Dedong Kang | |
| contact affiliation | Showa University |
| dataset submitter | |
Full Dataset Link List
| jPOST dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003576/ |
