PXD060057

PXD060057 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation
Description	JNKs play critical roles in neuronal damage associated with neurodegenerative disease and inhibitors of JNK1 have shown anxiolytic and anti-depressive effects in mice. In this study, we analyze the phosphoproteomes of hippocampus and nucleus accumbens in mice treated with DJNKI-1, a JNK inhibitor.
HostingRepository	PRIDE
AnnounceDate	2025-12-02
AnnouncementXML	Submission_2025-12-02_01:08:59.941.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dani Flinkman
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-22 02:57:14	ID requested
⏵ 1	2025-12-02 01:09:00	announced

Publication List

10.1016/j.nbd.2025.107207;
Hong Y, Siino V, Flinkman D, Deshpande P, Martinez SO, Fagerholm V, Varidaki A, Heemeryck P, Sourander C, James P, Coffey E, JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation. Neurobiol Dis, 218():107207(2026) [pubmed]

10.1016/j.nbd.2025.107207;

Hong Y, Siino V, Flinkman D, Deshpande P, Martinez SO, Fagerholm V, Varidaki A, Heemeryck P, Sourander C, James P, Coffey E, JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation. Neurobiol Dis, 218():107207(2026) [pubmed]

Keyword List

submitter keyword: None

submitter keyword: None

Contact List

Eleanor Coffey
contact affiliation	Turku Bioscience Centre, University of Turku and Åbo Akademi University
contact email	elecof@utu.fi
lab head
Dani Flinkman
contact affiliation	Turku Bioscience
contact email	dkflin@utu.fi
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD060057
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD060057

PRIDE project URI

Repository Record List

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