PXD060026

PXD060026 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	SFPQ Directs Histone H3.3 Deposition to R-Loops in DNA Repeats to Protect Genome Stability
Description	This study investigates the role of SFPQ protein interactions in contributing to genome stability. Proteomic analysis was conducted using immunoprecipitation to isolate specific proteins, followed by SDS-PAGE, tryptic digestion, and mass spectrometry to identify and characterize the interacting proteins involved in this process.
HostingRepository	PRIDE
AnnounceDate	2026-02-17
AnnouncementXML	Submission_2026-02-17_07:42:00.938.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Stefan Schoeftner
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Proteomics Analyzer

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-21 10:08:00	ID requested
⏵ 1	2026-02-17 07:42:01	announced

Publication List

10.1038/S41467-026-69479-W;

10.1038/S41467-026-69479-W;

Keyword List

submitter keyword: SFPQ, Replication stress, R-Loops

submitter keyword: SFPQ, Replication stress, R-Loops

Contact List

Stefan Schoeftner
contact affiliation	University of Trieste, Department of Life Sciences, Building C11; 2nd floor; room 245, Via Licio Giorgieri, 1, 34127 Trieste, Italy
contact email	sschoeftner@units.it
lab head
Stefan Schoeftner
contact affiliation	Università degli Studi di Trieste, Dipartimento di Scienze della Vita
contact email	sschoeftner@units.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD060026
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD060026

PRIDE project URI

Repository Record List

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