PXD059983

PXD059983 is an original dataset announced via ProteomeXchange.

Title	Proteome analysis of satellite cells from DMD and WT pigs
Description	Recent studies on the contribution of satellite cells (SC) to Duchenne muscular dystrophy (DMD) documented altered division capacities and impaired regeneration potential of SC in muscle tissue of DMD patients and animal models. Hence, it is crucial to unravel if SC-intrinsic effects trigger these deficiencies at pre-contractile stages of myogenesis rather than resulting consequently from the pathologic environment. Addressing this, we isolated SC from muscle biopsies of a porcine DMD model for cultivation and characterization.
HostingRepository	PRIDE
AnnounceDate	2025-06-30
AnnouncementXML	Submission_2025-06-29_16:23:16.266.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jan Bernd Stöckl
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-20 08:59:11	ID requested
⏵ 1	2025-06-29 16:23:17	announced

10.3390/cells14120892;

Franzmeier S, Chakraborty S, Mortazavi A, St, ö, ckl JB, Jiang J, Pfarr N, Sabass B, Fr, ö, hlich T, Kaufhold C, Stirm M, Wolf E, Schlegel J, Matiasek K, Multi-Modal Analysis of Satellite Cells Reveals Early Impairments at Pre-Contractile Stages of Myogenesis in Duchenne Muscular Dystrophy. Cells, 14(12):(2025) [pubmed]

submitter keyword: dystrophin, satellite cells,Duchenne muscular dystrophy

Thomas Fröhlich
contact affiliation	Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München
contact email	frohlich@genzentrum.lmu.de
lab head
Jan Bernd Stöckl
contact affiliation	Genzentrum der LMU München
contact email	stoeckl@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/06/PXD059983

PRIDE project URI

• PRIDE
  1. PXD059983
     1. Label: PRIDE project
     2. Name: Proteome analysis of satellite cells from DMD and WT pigs