PXD059873

PXD059873 is an original dataset announced via ProteomeXchange.

Title	Stoichiometric organisation of necrosome
Description	The necrosome is a key macromolecular platform that initiates the RIPK1/RIPK3-dependent programme of cell death, termed necroptosis. Necroptosis plays an important role in controlling inflammation and cell death in multicellular organisms. Here, we used quantitative mass spectrometry to decipher the composition of the CD95L/BV6-induced necrosome.
HostingRepository	PRIDE
AnnounceDate	2025-03-06
AnnouncementXML	Submission_2025-03-06_03:38:08.851.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thilo Kaehne
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deaminated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-16 02:57:32	ID requested
⏵ 1	2025-03-06 03:38:09	announced

Dataset with its publication pending

submitter keyword: stoichiometry,necrosome, AQUA

Prof. Dr. Thilo Kaehne
contact affiliation	Institute of Exptl. Internal Medicine Medical Faculty, University Magdeburg Leipzigerstr. 44 39120 Magdeburg, Germany
contact email	kaehne@med.ovgu.de
lab head
Thilo Kaehne
contact affiliation	University Magdeburg
contact email	kaehne@med.ovgu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/03/PXD059873

PRIDE project URI

• PRIDE
  1. PXD059873
     1. Label: PRIDE project
     2. Name: Stoichiometric organisation of necrosome