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PXD059795

PXD059795 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis of peripheral blood in 4 healthy controls and 4 patients with polycystic ovary syndrome
Description	In this study, 4 PCOS serum samples and 4 healthly controls were utilized for proteomic analysis. The UltiMate 3000 (Thermo Fisher Scientific, MA, USA) liquid chromatography system was connected to the timsTOF Pro 2, an ion-mobility spectrometry quadrupole time of flight mass spectrometer (Bruker Daltonik, Bremen, Germany). For comparative analysis of PCOS and healthy controls, FC> 1.2 and p-value <0.05 were selected as differential protein screening criteria. Deferentially expression proteins were analysised using gene ontology (GO) terms with Blast2GO software (http://www.blast2go.com/b2ghome).GO annotation results were plotted using R scripts. and matched against the Kyoto Encyclopedia of Genes and Genomes (KEGG) database by the KEGG Automatic Annotation Server (KAAS, https://www.genome.jp/tools/kaas/). P < 0.05 in Fisher’s exact test was considered significant. The STRING-DB protein interaction network was built using the STRING database (http://string-db.org/).
HostingRepository	iProX
AnnounceDate	2025-01-15
AnnouncementXML	Submission_2025-01-14_19:27:22.333.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenjing Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-14 19:27:07	ID requested
⏵ 1	2025-01-14 19:27:22	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: polycystic ovary syndrome

Contact List

Tizhen Yan
contact affiliation	Dongguan Maternal and Children Health Hospital
contact email	439078813@qq.com
lab head
Wenjing Wang
contact affiliation	Dongguan Maternal and Children Health Hospital
contact email	wangwenjing007@126.com
dataset submitter

Full Dataset Link List

iProX dataset URI