PXD059704
PXD059704 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | DMLL alleviates ulcerative colitis in mice |
| Description | The natural compound DMLL alleviates DSS-induced experimental colitis through modulating gut microbiota and metabolic dysbiosis. The phylum of Bacteroidota and genera of norank_f_Muribaculaceae and Ruminococcus with beneficial potential for UC were the major gut flora regulated by DMLL. In terms of microbiota-derived metabolites, DMLL primarily enriched tryptophan metabolites, secondary bile acids and nicotinamide that possess anti-inflammatory activity and proved protection for intestinal epithelial barrier, subsequently altered the metabolic pathways and improved the impaired host gut homeostasis. |
| HostingRepository | iProX |
| AnnounceDate | 2025-01-13 |
| AnnouncementXML | Submission_2025-05-05_22:06:35.497.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yan Cheng |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-01-12 21:30:09 | ID requested | |
| ⏵ 1 | 2025-05-05 22:06:35 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Metabolomics, Ulcerative colitis, Gut microbiota, Microbial metabolites |
Contact List
| Weifeng Zhu | |
|---|---|
| contact affiliation | Jiangxi University of Chinese Medicine |
| contact email | 19930220@jxutcm.edu.cn |
| lab head | |
| Yan Cheng | |
| contact affiliation | Jiangxi University of Chinese Medicine |
| contact email | chengyan_8304@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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