PXD059685

PXD059685 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics study of right atrium in patients with atrial fibrillation after coronary artery bypass grafting
Description	We performed 4D-labelfree quantitative proteomics analysis of right atrial appendage tissues from 5 patients with atrial fibrillation (AF) and 5 patients with sinus rhythm (SR) after CABG. A total of 2179,559 spectrums and 48,047 peptides were detected by mass spectrometry. Further, we identified 5002 proteins, of which the number of comparable proteins was 4166. Finally, compared with SR group, 108 proteins were up-regulated and 25 proteins were down-regulated in AF group (AF/SR > 1.5, P < 0.05).
HostingRepository	PRIDE
AnnounceDate	2025-08-11
AnnouncementXML	Submission_2025-08-11_14:47:59.427.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hai-Tao Hou
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF HT

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-12 14:37:13	ID requested
⏵ 1	2025-08-11 14:48:00	announced

Publication List

Zhang Y, Chen HX, Hou HT, Liu YQ, Chen Z, Yang Q, He GW, Atlas of lysine propionylation of human right atrium and ALDH6A1-NADH pathway in new-onset atrial fibrillation after coronary surgery. Commun Biol, 8(1):858(2025) [pubmed]
10.1038/s42003-025-08264-9;

Zhang Y, Chen HX, Hou HT, Liu YQ, Chen Z, Yang Q, He GW, Atlas of lysine propionylation of human right atrium and ALDH6A1-NADH pathway in new-onset atrial fibrillation after coronary surgery. Commun Biol, 8(1):858(2025) [pubmed]

10.1038/s42003-025-08264-9;

Keyword List

submitter keyword: proteomics, right atrial appendage, atrial fibrillation

submitter keyword: proteomics, right atrial appendage, atrial fibrillation

Contact List

Hou HT
contact affiliation	Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University & Chinese Academy of Medical Sciences, Tianjin, 300457, China
contact email	hhtpk007@163.com
lab head
Hai-Tao Hou
contact affiliation	Teda International Cardiovascular Hospital
contact email	hhtpk007@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD059685
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD059685

PRIDE project URI

Repository Record List

[ + ]