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PXD059684

PXD059684 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDeciphering the proteomic profile of the parasite Fasciola hepatica during host migration reveals new insights into early-stage infection
DescriptionThe project presents an in vivo mouse model coupled with quantitative SWATH-MS proteomics to study the early stages of Fasciola hepatica migration, focusing on the parasite's passage through the intestinal barrier to peritoneum(24 hours post-infection) and migration to the liver parenchyma (8 days post-infection). This approach aims to assess the proteomic changes in the parasite during these critical stages of infection.
HostingRepositoryPRIDE
AnnounceDate2025-06-05
AnnouncementXMLSubmission_2025-06-04_23:25:49.518.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMarta López-García
SpeciesList scientific name: Fasciola hepatica (Liver fluke); NCBI TaxID: 6192;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 6600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-12 12:54:12ID requested
12025-06-04 23:25:49announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: infection, migration ,Parasite, SWATH-MS, LC-MS/MS
Contact List
Mar Siles-Lucas
contact affiliationLaboratory of Helminth Parasites of Zoonotic Importance(ATENEA), Institute of Natural Resources and Agrobiology of Salamanca (IRNASA-CSIC), Spain
contact emailmmar.siles@irnasa.csic.es
lab head
Marta López-García
contact affiliationLaboratory of Helminth Parasites of Zoonotic Importance (ATENEA), Institute of Natural Resources and Agrobiology of Salamanca (IRNASA-CSIC), C/Cordel de Merinas 40-52, 37008 Salamanca, Spain
contact emailmarta.lopez@irnasa.csic.es
dataset submitter
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Dataset FTP location
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PRIDE project URI
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