⮝ Full datasets listing

PXD059676

PXD059676 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEffects of Heat Stress on Liver Function Damage and Mechanisms in Pregnant Sows
DescriptionThis study aims to investigate the effects and mechanisms of heat stress (HS) on the physiological functions of the liver in primiparous sows during early pregnancy.In the experimental design, we exposed early pregnant sows to HS (high temperature and humidity environment) and TN (normal environment) conditions. Through blood gas analysis, endocrine index detection, biochemical detection, and histological immunofluorescence analysis, we evaluated the systemic physiological responses and liver damage in sows under HS.Additionally, the study carried out preliminary transcriptomics, proteomics, and metabolomics analyses of the liver to reveal the molecular mechanisms underlying liver dysfunction caused by HS.
HostingRepositoryPRIDE
AnnounceDate2025-07-07
AnnouncementXMLSubmission_2025-07-06_16:23:18.176.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitter振浩 温
SpeciesList scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-12 00:59:56ID requested
12025-07-06 16:23:19announced
Publication List
10.3390/antiox14060623;
Chai J, Wen Z, Chen L, Pu Q, Luo T, Wu X, Ma Z, Luo Z, Luo J, Wang J, Multi-Omics Analysis of Chronic Heat Stress-Induced Biological Effects, Liver Injury, and Heat Tolerance Mechanisms via Oxidative and Anti-Inflammatory Pathways in Early-Pregnancy Sows. Antioxidants (Basel), 14(6):(2025) [pubmed]
Keyword List
ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: heat stress;liver cell damage;embryo implantation
Contact List
wen zhenhao
contact affiliationSchool of Animal Science and Technology, Genetic Breeding and Reproduction Laboratory, Southwest University, China;Chongqing Academy of Animal Husbandry Sciences, Pig Breeding Research Institute, China
contact emailwenzhenhao1352590@163.com
lab head
振浩 温
contact affiliationStudent
contact emailwenzhenhao1352590@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD059676
PRIDE project URI
Repository Record List
[ + ]