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PXD059554

PXD059554 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProbing the trypanosome nuclear pore by TurboID proximity labelling – Part3
DescriptionPrevious BioID experiments targeting the nucleoporin (NUP) NUP158 (PMID: 36410438; PXD031245), as well as NUP110, NUP76, NUP96 (PMID: 39206942; PXD047268)and NUP75, transport factors MEX67 and Ran(PXD055934), indicated that proximity labelling delivers highly specific interactome data in the confined localisation of the nuclear pore, with a labelling radius well below the size of the nuclear pore. The resulting proximity data allowed to assign NUPs and nuclear transport factors to specific subregions of the pore. Here we extended this approach to target NUP98.
HostingRepositoryPRIDE
AnnounceDate2025-05-07
AnnouncementXMLSubmission_2025-05-07_06:26:51.610.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMartin Zoltner
SpeciesList scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-01-08 07:13:31ID requested
12025-05-07 06:26:52announced
Publication List
10.1371/journal.pbio.3003024;
Gabiatti BP, Krenzer J, Braune S, Kr, ü, ger T, Zoltner M, Kramer S, Detailed characterisation of the trypanosome nuclear pore architecture reveals conserved asymmetrical functional hubs that drive mRNA export. PLoS Biol, 23(2):e3003024(2025) [pubmed]
Keyword List
submitter keyword: TurboID, proximity labeling, nuclear pore,Trypanosoma brucei
Contact List
Martin Zoltner
contact affiliationCharles University in Prague Faculty of Science, Department of Parasitology BIOCEV Průmyslová 595 252 50 Vestec Czech Republic
contact emailzoltnerm@natur.cuni.cz
lab head
Martin Zoltner
contact affiliationDivision of Biological Chemistry & Drug Discovery School of Life Sciences University of Dundee Dundee DD1 5EH
contact emailzoltnerm@natur.cuni.cz
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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