PXD059554 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Probing the trypanosome nuclear pore by TurboID proximity labelling – Part3 |
Description | Previous BioID experiments targeting the nucleoporin (NUP) NUP158 (PMID: 36410438; PXD031245), as well as NUP110, NUP76, NUP96 (PMID: 39206942; PXD047268)and NUP75, transport factors MEX67 and Ran(PXD055934), indicated that proximity labelling delivers highly specific interactome data in the confined localisation of the nuclear pore, with a labelling radius well below the size of the nuclear pore. The resulting proximity data allowed to assign NUPs and nuclear transport factors to specific subregions of the pore. Here we extended this approach to target NUP98. |
HostingRepository | PRIDE |
AnnounceDate | 2025-05-07 |
AnnouncementXML | Submission_2025-05-07_06:26:51.610.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Martin Zoltner |
SpeciesList | scientific name: Trypanosoma brucei; NCBI TaxID: 5691; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2025-01-08 07:13:31 | ID requested | |
⏵ 1 | 2025-05-07 06:26:52 | announced | |
Publication List
10.1371/journal.pbio.3003024; |
Gabiatti BP, Krenzer J, Braune S, Kr, ü, ger T, Zoltner M, Kramer S, Detailed characterisation of the trypanosome nuclear pore architecture reveals conserved asymmetrical functional hubs that drive mRNA export. PLoS Biol, 23(2):e3003024(2025) [pubmed] |
Keyword List
submitter keyword: TurboID, proximity labeling, nuclear pore,Trypanosoma brucei |
Contact List
Martin Zoltner |
contact affiliation | Charles University in Prague Faculty of Science, Department of Parasitology BIOCEV Průmyslová 595 252 50 Vestec Czech Republic |
contact email | zoltnerm@natur.cuni.cz |
lab head | |
Martin Zoltner |
contact affiliation | Division of Biological Chemistry & Drug Discovery School of Life Sciences University of Dundee Dundee DD1 5EH |
contact email | zoltnerm@natur.cuni.cz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD059554 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD059554
- Label: PRIDE project
- Name: Probing the trypanosome nuclear pore by TurboID proximity labelling – Part3