PXD059554

PXD059554 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Probing the trypanosome nuclear pore by TurboID proximity labelling – Part3
Description	Previous BioID experiments targeting the nucleoporin (NUP) NUP158 (PMID: 36410438; PXD031245), as well as NUP110, NUP76, NUP96 (PMID: 39206942; PXD047268)and NUP75, transport factors MEX67 and Ran(PXD055934), indicated that proximity labelling delivers highly specific interactome data in the confined localisation of the nuclear pore, with a labelling radius well below the size of the nuclear pore. The resulting proximity data allowed to assign NUPs and nuclear transport factors to specific subregions of the pore. Here we extended this approach to target NUP98.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_06:26:51.610.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Martin Zoltner
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-08 07:13:31	ID requested
⏵ 1	2025-05-07 06:26:52	announced

Publication List

10.1371/journal.pbio.3003024;
Gabiatti BP, Krenzer J, Braune S, Kr, ü, ger T, Zoltner M, Kramer S, Detailed characterisation of the trypanosome nuclear pore architecture reveals conserved asymmetrical functional hubs that drive mRNA export. PLoS Biol, 23(2):e3003024(2025) [pubmed]

10.1371/journal.pbio.3003024;

Gabiatti BP, Krenzer J, Braune S, Kr, ü, ger T, Zoltner M, Kramer S, Detailed characterisation of the trypanosome nuclear pore architecture reveals conserved asymmetrical functional hubs that drive mRNA export. PLoS Biol, 23(2):e3003024(2025) [pubmed]

Keyword List

submitter keyword: TurboID, proximity labeling, nuclear pore,Trypanosoma brucei

submitter keyword: TurboID, proximity labeling, nuclear pore,Trypanosoma brucei

Contact List

Martin Zoltner
contact affiliation	Charles University in Prague Faculty of Science, Department of Parasitology BIOCEV Průmyslová 595 252 50 Vestec Czech Republic
contact email	zoltnerm@natur.cuni.cz
lab head
Martin Zoltner
contact affiliation	Division of Biological Chemistry & Drug Discovery School of Life Sciences University of Dundee Dundee DD1 5EH
contact email	zoltnerm@natur.cuni.cz
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD059554
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD059554

PRIDE project URI

Repository Record List

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