PXD059538

PXD059538 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic Profiling of AVF Remodeling in Mice
Description	This project investigates proteomic changes in vascular remodeling at post-operative day 7 in male mice subjected to arteriovenous fistula (AVF) creation compared to sham-operated controls. Using bulk sequencing, differentially expressed proteins and enriched pathways will be identified to understand the molecular mechanisms underlying early AVF remodeling. The study aims to uncover key proteins and signaling pathways driving these processes, providing insights into potential therapeutic targets to improve AVF maturation and long-term outcomes.
HostingRepository	PRIDE
AnnounceDate	2025-04-19
AnnouncementXML	Submission_2025-04-19_08:33:55.478.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD059538
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Luis Gonzalez
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-08 00:15:03	ID requested
⏵ 1	2025-04-19 08:33:56	announced

Publication List

Gonzalez LA, Zhang W, Bai H, Taniguchi R, Ramachandra AB, Jovin DG, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron RI, Humphrey JD, Martin KA, Kyriakides TR, Dardik A, Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. Am J Physiol Heart Circ Physiol, 328(6):H1147-H1167(2025) [pubmed]
10.6019/PXD059538;
10.1152/ajpheart.00661.2024;

Gonzalez LA, Zhang W, Bai H, Taniguchi R, Ramachandra AB, Jovin DG, Ohashi Y, Nguyen M, Thaxton C, Yatsula B, Vazquez-Padron RI, Humphrey JD, Martin KA, Kyriakides TR, Dardik A, Sustained tenascin-C expression drives neointimal hyperplasia and promotes aortocaval fistula failure. Am J Physiol Heart Circ Physiol, 328(6):H1147-H1167(2025) [pubmed]

10.6019/PXD059538;

10.1152/ajpheart.00661.2024;

Keyword List

submitter keyword: AVF

submitter keyword: AVF

Contact List

Alan Dardik
contact affiliation	Department of Surgery, Yale School of Medicine, New Haven, CT
contact email	alan.dardik@yale.edu
lab head
Luis Gonzalez
contact affiliation	Yale University
contact email	luis.gonzalez@yale.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD059538
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/04/PXD059538

PRIDE project URI

Repository Record List

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