PXD059457

PXD059457 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Dual Roles of hABCB1 in Drug Resistance and Immune Evasion: Implications for Lung Cancer Therapy
Description	Standard chemotherapy for lung cancer often leads to drug resistance, posing a significant clinical challenge. A major mechanism of resistance is overexpression of P-glycoprotein (P-gp), encoded by the human ATP-binding cassette subfamily B member 1 (hABCB1) gene, functioning as a drug efflux transporter. In this study, we aimed to investigate the dual role of hABCB1 overexpression in mediating resistance to chemotherapy and natural killer (NK) cell-mediated cytotoxicity in lung cancer.
HostingRepository	MassIVE
AnnounceDate	2025-01-24
AnnouncementXML	Submission_2025-01-24_21:36:44.790.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Geul Bang
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-06 01:35:18	ID requested
⏵ 1	2025-01-24 21:36:45	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: drug resistance, DatasetType:Proteomics

submitter keyword: drug resistance, DatasetType:Proteomics

Contact List

Geul Bang
contact affiliation	Korea Basic Science Institute
contact email	bangree@kbsi.re.kr
lab head
Geul Bang
contact affiliation	Korea Basic Science Institute
contact email	bangree@kbsi.re.kr
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000096780/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v06/MSV000096780/