PXD059345

PXD059345 is an original dataset announced via ProteomeXchange.

Title	Confirmation of the phosphorylation sites of human PhK
Description	The activity of PhK is regulated by phosphorylation, and we utilized single-particle cryo-electron microscopy to solve the high-resolution structures of human PhK under phosphorylation and calcium ion activation. To gain a deeper insight into the phosphorylation sites following PKA treatment, we employed tandem mass spectrometry for precise localization of the phosphorylation sites within PhK.
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_05:56:54.231.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ruifang Ma
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2025-01-01 00:39:24	ID requested
⏵ 1	2025-05-07 05:56:55	announced

10.1038/s41467-025-58363-8;

Ma R, Du B, Shi C, Wang L, Zeng F, Han J, Guan H, Wang Y, Yan K, . Nat Commun, 16(1):3020(2025) [pubmed]

submitter keyword: Phosphorylation sites，PhK

Kaige Yan
contact affiliation	School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, Guangdong, China
contact email	yankg@sustech.edu.cn
lab head
Ruifang Ma
contact affiliation	Southern University of Science and Technology
contact email	marf@sustech.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD059345

PRIDE project URI

• PRIDE
  1. PXD059345
     1. Label: PRIDE project
     2. Name: Confirmation of the phosphorylation sites of human PhK