PXD059321
PXD059321 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | In-depth Spatial Proteomics for Whole Tissue Profiling by Sparse Sampling Strategy |
| Description | To achieve a deep quantitative proteomic profiling of whole tissue with the spatial localization preserved, we designed an untargeted spatial proteomics workflow with a sparse sampling strategy. We combined a computational approach and MS-based proteomics analysis to localize high-throughput proteome mapping within a tissue by microdissecting the slices into a series of parallel strips with different angles, that allow subsequent image reconstruction. We successfully reconstructed a whole-tissue mapping in a mouse brain, consisting of 8,645 protein distributions and expressions with a spatial resolution of approx. 300 μm. |
| HostingRepository | iProX |
| AnnounceDate | 2024-12-31 |
| AnnouncementXML | Submission_2024-12-31_00:23:45.003.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ritian Qin |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-12-31 00:22:49 | ID requested | |
| ⏵ 1 | 2024-12-31 00:23:45 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Spatial proteomics, sparse sampling, LC-MS/MS |
Contact List
| Weijie Qin | |
|---|---|
| contact affiliation | National Center for Protein Sciences (Beijing) |
| contact email | aunp_dna@126.com |
| lab head | |
| Ritian Qin | |
| contact affiliation | Tsinghua University |
| contact email | qinritian97@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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